discordant

Not in accord or harmony; conflicting, incompatible.

Of people: disagreeing with each other; dissenting, quarrelsome.

Of sounds: harsh, jarring; specifically (music), of musical notes or tunes: not in harmony; dissonant, inharmonious.

Of a rock formation or other land feature, or its alignment: cutting across or transverse to neighbouring features.

Of a coastline: having bands of different types of rock running transversely to the coast, leading to the formation of alternating bays and headlands.

Of two similar subjects, especially twins: differing in some characteristic.

Ellipsis of serodiscordant (“of a couple: with one partner HIV positive and the other HIV negative”).

Of figures, etc.: having opposite signs (for example, positive and negative).