lose it
verb
RareNot in standard dictionaries
1
To become explosively angry; to lose one's temper.
2
To feel devastated, or distraught, especially when one's sadness is overwhelming.
3
To begin to laugh uncontrollably.
4
To lose one's mind, go crazy.
5
To cease to have a skill or ability, to lose one's touch, to be washed up.
6
To lose control of a situation.
7
Used other than figuratively or idiomatically: see lose, it.
Thesaurus
#informal